Dr Jenny Harries, Chief Executive of UKHSA, said: We are continuing our efforts to understand the effect of this variant on transmissibility, severe disease, mortality, antibody response and vaccine efficacy. Until we have this evidence, we must exercise the highest level of caution in drawing conclusions about any significant risks to peoples health. The UK Health Security Agency (UKHSA) has published a new variant technical briefing containing an updated Omicron risk assessment, alongside analysis on vaccine efficacy, sub-lineages and symptoms. There is currently no evidence of community transmission within the UK. BA.2 attacking abdomen instead of lungs. Work is underway to identify any links to travel. UKHSAwill continue to carry out laboratory and epidemiological investigations to better understand the characteristics of this variant. In England, the infection rate increased in those aged 25 years to 49 years and those aged 70 years and over in the week ending 21 February 2023. This is consistent with analysis published yesterday by Imperial College London and the University of Edinburgh. As always, the booster vaccine remains the best protection against infection. The UK Health Security Agency (UKHSA) has published the latest Variant Technical Briefing. "We must remain vigilant and take up vaccinations. In the last week, VUI-21OCT-01 accounted for approximately 6% of all Delta cases. ; The incubation time (time to onset of symptoms) is a bit shorter: 3 days. The Omicron variant sub-lineage known as BA.2 has been designated a variant under investigation ( VUI-22JAN-01) by the UK Health Security Agency (UKHSA). Any variants showing evidence of spread are rapidly assessed. BA.2 has been under close . The data once again shows that coming forward for your jab, particularly your third dose, is the best way of protecting yourself and others against infection and severe disease. In this analysis, the risk of hospitalisation is lower for Omicron cases with symptomatic or asymptomatic infection after 2 and 3 doses of vaccine, with an 81% (95% confidence interval 77 to 85%) reduction in the risk of hospitalisation after 3 doses compared to unvaccinated Omicron cases. It is therefore vital that people continue to exercise caution in order to limit the transmission of the virus. Now more countries, particularly in Asia and Europe, are reporting an increase in cases driven by BA.2. That contrasts to Denmark, where it has become dominant. Professor Susan Hopkins, Chief Medical Advisor at UKHSA said: It is clear that the increasing prevalence of Omicron BA.4 and BA.5 are significantly increasing the case numbers we have observed in recent weeks. Previous updates were published by Public Health England. Work is underway to identify any links to travel. The most affected local authorities are West Northamptonshire, where there are 49 confirmed cases and 68 SGTF, and Manchester, where there are 7 confirmed cases and 61 SGTF. Early data shows that young children who are hospitalised experience mild illness and are discharged after short stays in hospital. Earlier COVID-19 variants affected the lung tissue more and had a higher likelihood of causing pneumonia and other severe outcomes. Fourteen people are reported to have died within 28 days of an Omicron diagnosis, ranging in age from 52 to 96 years old. One individual diagnosed in hospital has sadly died. This is still a very small number of cases but is being investigated carefully to understand whether it is related to travel, any other variant or whether there is evidence of spread of Omicron beginning in the community. More detail will be available in UKHSAs regular variant technical briefings. Vaccination is critical to help us bolster our defences against this new variant please get your first, second, third or booster jab without delay. Wear a mask in crowded places, including public transport and shops, to ensure we all help break the chains of transmission and slow the spread of this new variant. It has been designated a "variant under investigation" by British health authorities, meaning they are keeping a close watch on it, but are not overly concerned by it. The risk assessment conducted by UKHSA together with academic partners found that CH.1.1 and XBB.1.5 are currently the variants most likely to take over from BQ.1 as the next dominant variant in the UK, unless further novel variants arise. However, vaccinated people are still less likely to get infected than unvaccinated individuals, and they are also less likely to pass it on. Although there was a rapid increase in SARS-CoV-2 infections in care homes during December 2021 in line with case rises in the community, there has not been an associated increase in hospital admissions. As part of UKHSAs routine genomic surveillance, approximately 15 to 20% of all positive PCR tests are also sent for sequencing. It is vital that everyone over the age of 40 who is eligible for a booster jab comes forward as soon as possible to get increased protection against this new variant. Read about our approach to external linking. Work is underway to identify any links to travel to Southern Africa. Top of the list with a prevalence of 80. We constantly assess the genetic diversity within the known variants of concern (VOCs) to inform our ongoing public health response to the pandemic. The UK Health Security Agency (UKHSA) has identified 8 further cases of COVID-19 with mutations consistent with B.1.1.529 in England, in addition to the previous 5 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529. Of these, 20 were in England, 3 in Scotland and 1 in Wales. BA.2, also known as "stealth omicron," is considered a subvariant of omicron. Dr Meera Chand, Director of Clinical and Emerging Infection at UKHSA, said: It is not unexpected to see new variants of SARS-CoV-2 emerge. Experts say BA.2 has extensive mutations and is about 40 percent more infectious than the original Omicron variant. The individual tested positive after travel to the UK and is linked to travel to Southern Africa. This edition includes an update on the current circulating lineages, including several cases of Omicron BA.4 and BA.5 which have been detected in the UK. The same happened with Omicron, which includes the lineages BA.1, BA.2, BA.3 and B.1.1.529. A booster dose for everyone over 18 years is now recommended and will be available at a minimum of 3 months from your last primary course jab. People suffering From the Omicron BA2 variant said they had fever and body Aches. Since then, several sub-variants of Omicron surfaced, including BA.2, BA.3, BA.4, and BA.5. Hospital cases are also rising, but vaccines are still helping to stop many severe. Thats why its critical that anyone with COVID-19 symptoms isolates and gets a PCR test immediately. Please come forward to receive your booster as soon as possible. A further 3 cases have been identified in Scotland, bringing the total to 13. More investigation is required to fully determine the extent of these mutations impact. The BA.2 subvariant has been referred to as stealth Omicron because it contains genetic mutations that can make it harder to distinguish from the . It is not clear where BA.2 originated, but it was first detected in the Philippines in November. We have now identified cases in the East Midlands, East of England, London, North East, North West, South East, South West and West Midlands. Protection against hospitalisation from vaccines is good against the Omicron variant. While evidence is still emerging, so far it does not appear this variant causes more severe disease or renders the vaccines currently deployed any less effective. As of 20 October, there were 15,120 cases of VUI-21OCT-01 confirmed by whole genome sequences in England since it was first detected in July. And in England, more than 1,000 confirmed cases of BA.2 have been identified, according to the UK Health Security Agency (UKHSA). Dont worry we wont send you spam or share your email address with anyone. The risk assessment also suggests that Omicron displays a reduction in protection offered by having had a previous infection or vaccination. UKHSA is carrying out targeted testing at locations where the positive cases were likely to be infectious. Since then, the Centers for Disease Control and Prevention (CDC) has classified two subvariants, BA.1.1 and BA.2. There are small numbers of cases in the UK and this designation is intended to allow investigation into the specific properties of this variant. There are differences in the populations that have received different vaccines. News stories, speeches, letters and notices, Reports, analysis and official statistics, Data, Freedom of Information releases and corporate reports. However, increases in SGTF can give a useful early indication of variant spread. Overall numbers of ICU admissions have decreased over time, but where data was available admissions with Omicron have increased from 9% to more than 50% in the most recent week. The Omicron BA.2 subvariant is fast becoming the dominant strain of COVID-19, with symptoms similar to previous strains of the virus. Apart from dizziness and fatigue, some other signs of BA.2 Omicron Variants include: Fever and body aches Loss of taste Nausea or Vomiting Abdominal pain Fever Extreme fatigue Coughing Sore throat Muscular fatigue Elevated heart rate Breathless in severe cases readmore End of Story After 2 doses, vaccine effectiveness was 9% and 13% respectively for BA.1 and BA.2, after 25+ weeks. You can change your cookie settings at any time. While growth rates can be overestimated in early analyses of a new variant, the apparent growth advantage is currently substantial. As with previous variants, experts believe vaccines will continue to be highly effective against severe illness, hospitalisation, and death. Studies of contacts show that Omicron is transmitting more effectively than Delta. According to Boden-Albala said, those symptoms may include the following: Fever Chills Fatigue Cough Body aches Shortness of breath Sore throat Additionally, some people may report upper. We now know that BA.2 has an increased growth rate which can be seen in all regions in England. Runny nose (especially in combination with loss of smell) A runny nose is a universal sign of cold, flu and now COVID-19. The genome of VUI-21OCT-01 does not have many mutations compared to Delta. Analysis by the UKHSA suggests it could be substantial, although there is a risk of over-estimating growth advantage in the early stages. Work is underway to identify any links to travel to Southern Africa. Thats why its critical that anyone with COVID-19 symptoms isolates and gets a PCR test immediately. Yet fears of another Omicron wave in the United States may be. The BBC is not responsible for the content of external sites. The UK Health Security Agency (UKHSA) can confirm that 10 people have been hospitalised with the Omicron variant in England; the individuals were diagnosed on or before admission. As we learn to live safely with COVID-19, there are actions we can all take to help reduce the risk of catching COVID-19 and passing it on to others. The individuals that have tested positive are not connected to each other and are not linked to the previously confirmed cases. The UK Health Security Agency (UKHSA) has identified 7 further cases of COVID-19 with mutations consistent with B.1.1.529 in England, in addition to the previous 22 confirmed cases of the SARS-CoV-2 variant known as B.1.1.529. Currently, the Omicron variant has BA.1, BA.2, BA.3, and B.1.1.529 sub-variants, of which the BA.1 was dominant a few months before, and scientists have recently warned about the BA.2 sub-variant . But it is worth noting that Denmark has seen similar trends in terms of hospital admissions and intensive care as the UK has, suggesting BA.2 does not mark a sea-change in severity. It is testament to the diligence and scientific expertise of my colleagues at UKHSA, and the genomic sequencing capacity developed through the pandemic, that this new variant has been identified and analysed so quickly. A further case has been identified in Scotland, bringing the total to 10. There is no data to suggest that BA.2 leads to more severe disease than previous Omicron sub-variants. With the original version of the omicron variant, which swept across the U.S. at a dizzying speed last winter, the loss of taste and smell was not as common as with the earlier alpha and delta variants. Susan Hopkins, Chief Medical Advisor at UKHSA, said: This latest set of analysis once again demonstrates that a booster dose of the vaccine provides you with significant protection against hospitalisation from Omicron. The data suggests this risk is significantly reduced following a booster vaccine, so I urge everyone to take up their booster when eligible. These early findings should be interpreted with caution as transmission data and dynamics can fluctuate, meaning that early findings can change quickly when new variants are identified. They say its possible that the virus has now changed its pattern and is affecting the stomach. The pace of sharing sequences by India is very slow, median days from collection to deposition is 69 days according to GISAID. Congestion. Latest updates on SARS-CoV-2 variants detected in the UK. As with other kinds of variant, most will die off relatively quickly. It is important that everyone ensures that they are up to date with vaccinations offered as they remain our best form of defence against severe illness. These are potentially biologically significant mutations which may change the behaviour of the virus with regards to immune escape, transmissibility or susceptibility to treatments, but this has not been proven. Dr Meera Chand, Director of Clinical and Emerging Infections at UKHSA, said: The reclassification of these variants as variants of concern reflects emerging evidence on the growth of BA.4 and BA.5 internationally and in the UK. UKHSAis carrying out targeted testing at locations where the positive cases were likely to be infectious. Whilst there are insufficient data to quantify either vaccine effectiveness or risk of reinfection in the UK exactly, the observed growth, case distribution and early analyses in both South Africa and the UK are consistent with some loss of immune protection against infection. The UK Health Security Agency (UKHSA) has published a new variant technical briefing containing updated analysis on Omicron hospitalisation risk and vaccine efficacy against symptomatic disease and hospitalisation. Our advanced sequencing capabilities enable us to find variants and take rapid action to limit onward spread. Twoto4 weeks after a booster dose, vaccine effectiveness ranged from around 65 to 75%, dropping to 55 to 70% at 5 to 9 weeks and 40 to 50% from 10+ weeks after the booster. There is insufficient data to make any assessment of protection against severe disease, or to assess the severity of illness caused by Omicron. Further studies are underway in the UK and abroad. There have been recent reports of people who experience symptoms like those of viral meningitis, an inflammation of the brain and spinal cord membranes. Updated analysisshows theadditional incremental benefit from each vaccine exposureincluding for boosters, even in those who have had prior infection. Of these, XD and XF are recombinants of Delta and Omicron BA.1, while XE is a recombinant of Omicron BA.1 and BA.2. 2 or Stealth Omicron causes. The latest version raising alarms is an emerging subvariant of Omicron called BA.2. Genome sequencing among the states is not always fair. pic.twitter.com/ESQupxUet4. Vaccination is critical to help us bolster our defences against becoming severely ill from this new variant please get your first, second, third or booster jab without delay. Other countries that have uploaded more than 100 samples are India (530), Sweden (181), and Singapore (127). This is more promising data which reinforces just how important vaccines are. There are indications of a small rise in children admitted to hospital, but these early signals need further investigations before we can draw any conclusions about whether Omicron causes more severe illness in children. Stay at home if you have any respiratory symptoms or a fever and limit contact with others until you are feeling better, particularly if they are likely to be at greater risk if they contract COVID-19. Health and Social Care Secretary, Sajid Javid, said: We are learning to live with this virus and thanks to our world-leading surveillance system we can rapidly detect and carefully monitor any genetic changes to COVID-19. UKHSAis acting to get scientific information available as quickly as possible in order to inform the right balance of interventions to prevent transmission and protect lives. The Omicron variant of Covid-19 includes the lineages BA.1, BA.2, BA.3 and B.1.1.529. Increased case detection through focused contact tracing has led to more cases of the Omicron variant being identified and confirmed, as we have seen in other countries globally. One study has suggested that it may be difficult to identify this variant . Everybody who is contacted or has symptoms should take a PCR test as soon as possible, even if they have received a positive COVID-19 PCR test within the last 90 days. Of 5,153 individuals identified with an Omicron infection between 1 November and 11 December 2021, 305 were linked to a previous confirmed infection and had an interval from the previous positive test of 90 days or more. There will be a coprimary endpoint : Neutralizing antibody titers against the SARS-CoV-2 variant of most prominent public health interest according to pandemic evolution (among D614G, B.1.351, Omicron sub-variants BA.4-5, BQ1.1 and XBB or another recent variant) and against one of the variant targeted by the vaccines. There are also hybrid strains, such as XE, which is a combination of BA.1 and BA.2 By Alex Finnis Professor Susan Hopkins, Chief Medical Advisor, UKHSA said: Recombinant variants are not an unusual occurrence, particularly when there are several variants in circulation, and several have been identified over the course of the pandemic to date. Dr Chand said: "So far, there is insufficient evidence to determine whether BA.2 causes more severe illness than Omicron BA.1. UKHSA has also released a variant risk assessment for Omicron BA.4 and BA.5, summarising the emerging epidemiology and laboratory evidence. A preliminary assessment did not find evidence of a difference in vaccine effectiveness against symptomatic disease for BA.2 compared to BA.1. What are the most common symptoms of Omicron BA.2? As previously published, data continues to show vaccine effectiveness against hospitalisation for Omicron remains high. So far, there is insufficient evidence to determine whether BA.2 causes more severe illness than Omicron BA.1, but data is limited and UKHSA continues to investigate.
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